PurKine Endotoxin Removal Kit (polymyxin B)

- High capacity—More than 2, 000, 000 EU/mL to eliminate >99% of endotoxins.
- High performance—Protein recovery is more than 85%.Reducing final EU concentration to 0.1 EU/mL
- Cost-effective—No performance decrease after at least five repeated uses of the same batch of resin.
- Flexible—available in multiple formats including bulk resin, spin columns and complete kits.

PurKine Endotoxin Removal Resin is effective for reducing endotoxin levels in protein samples. Endotoxins, also known as lipopolysaccharides or LPS, are cell membrane components of Gram-negative bacteria (e.g. E. coli). Endotoxins strongly influence transfection of DNA into primary cells and sensitive cultured cells, and increased endotoxin levels lead to sharply reduced transfection efficiencies. The Resin consists of 90um beads of cross-linked 4% agarose, to which modified polymyxin B has been coupled. The portfolio allow optimization of process for maximum protein yield, stability and solubility. Tests also confirm that no decrease in performance occurs after at least five repeated uses. The PurKine Endotoxin Removal Resin is also available as prepacked spin column and kit formats.