G-418 (disulfate)

ArtNr	HY-17561-500mg
Hersteller	MedChem Express
CAS-Nr.	108321-42-2
Menge	500 mg
Quantity options	10 mM/1 mL 1 g 500 mg 5 g
Kategorie	Inhibitors & Compound Libraries Small Molecules
Typ	Inhibitors
Specific against	other
Purity	99.94
Citations	[1]Giordano-Santini R, et al. An antibiotic selection marker for nematode transgenesis. Nat Methods. 2010;7(9):721-723.\|[2]Volarevic M, et al. A novel G418 conjugate results in targeted selection of genetically protected hepatocytes without bystander toxicity. Bioconjug Chem. 2007;18(6):1965-1971.\|[3]Kwon KM, et al. Disialyl GD2 ganglioside suppresses ICAM-1-mediated invasiveness in human breast cancer MDA-MB231 cells. Int J Biol Sci. 2017;13(3):265-275. Published 2017 Feb 12.\|[4]Davies J, et al. A new selective agent for eukaryotic cloning vectors. Am J Trop Med Hyg. 1980;29(5 Suppl):1089-1092. Acta Pharmacol Sin. 2025 Nov 1. Adv Healthc Mater. 2025 Apr;14(10):e2404501. Adv Sci (Weinh). 2025 Apr;12(13):e2404961. Adv Sci (Weinh). 2025 Nov 3:e13380. Am J Cancer Res. 2021 May 15;11(5):2062-2080. Biologics. 2025 Aug 12:19:443-462. BMC Complement Med Ther. 2024 Nov 16;24(1):400. Cancer Commun (Lond). 2023 Jan;43(1):123-149. Cancer Res. 2023 Apr 4;83(7):1048-1061. Cell Death Differ. 2020 Jun;27(6):1981-1997. Cell Death Dis. 2020 Jun 4;11(6):420. Cell Death Dis. 2019 May 28;10(6):413. Cell Rep. 2020 Oct 20;33(3):108287. Cell Rep. 2021 Mar 30;34(13):108906. Cell Rep. 2021 Sep 21;36(12):109739. Cell Rep. 2022 Oct 25;41(4):111561. Chemosphere. 2024 Oct:366:143350. Drug Resist Updat. 2026 Jan:84:101319. Emerg Microbes Infect. 2023 Dec;12(2):2261556. Environ Toxicol. 2024 Sep;39(9):4447-4458. Eur J Pharmacol. 2025 May 15:995:177418. Exp Mol Med. 2025 Nov;57(11):2686-2698. Hum Cell. 2022 Sep;35(5):1475-1486. Int J Biol Macromol. 2025 Dec;333(Pt 1):148831. Int J Biol Macromol. 2025 Sep 17;329(Pt 1):147753. J Agric Food Chem. 2022 Apr 6;70(13):3989-3999. J Biol Chem. 2023 May;299(5):104621. J Cell Mol Med. 2023 Apr;27(7):962-975. J Ethnopharmacol. 2025 Jun 2:120086. J Genet Genomics. 2021 Feb 20;48(2):134-146. Life Sci. 2024 Jun 1:346:122626. Med Oncol. 2021 Nov 10;39(1):10. Mol Cell. 2023 Dec 7;83(23):4370-4385.e9. Nature. 2023 Jun;618(7966):862-870. Oxid Med Cell Longev. 2022 Jan 28;2022:8168988. Patent. US20240299557A1. Protein Cell. 2025 Feb 18:pwaf014. Purdue University. 2025. Redox Biol. 2025 Aug 27:86:103847. Research Square Preprint. 2020 Jun. Research Square Preprint. 2021 Nov. Research Square Print. 2023 Feb 21. Sci Adv. 2024 Aug 16;10(33):eado1533. Sci Rep. 2025 Jul 2;15(1):23651. Theranostics. 2022 Jan 1;12(3):1187-1203. Transl Cancer Res. 2023 Jan 30;12(1):150-162. Transl Psychiatry. 2025 Apr 2;15(1):116. Acta Pharmacol Sin. 2023 Oct;44(10):2103-2112. Biochem Pharmacol. 2025 Sep 13;242(Pt 2):117337. Biochem Pharmacol. 2026 Jan;243(Pt 2):117529. Cell Biosci. 2025 Apr 13;15(1):46. Cell Mol Biol Lett. 2024 Feb 17;29(1):26. FASEB J. 2023 Nov;37(11):e23195. Research Square Preprint. 2023 Jul 11. SSRN. 2024 Jun 19.
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ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Geneticin sulfate,Antibiotic G-418 sulfate
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Natural Products
Manufacturer - Category	Reference compound / Active compounds; Natural Products
Manufacturer - Targets	Antibiotic; Bacterial
Manufacturer - HS Code	H302, H315, H319, H335
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, stored under nitrogen, away from moisture)
Molecular Weight	692.71
Product Description	G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells[1].
Manufacturer - Research Area	Infection
Solubility	H2O : 100 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Clinical information	No Development Reported
Isoform	Aminoglycoside
UNSPSC Code	12352005
Precautionary	H302, H315, H319, H335

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