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G-418 (disulfate)

G-418 (disulfate)

Item no.	HY-17561-500mg
Manufacturer	MedChem Express
CASRN	108321-42-2
Amount	500 mg
Quantity options	10 mM/1 mL 1 g 500 mg 5 g
Category	Inhibitors & Compound Libraries Small Molecules
Type	Inhibitors
Specific against	other
Purity	99.75
Citations	[1]Giordano-Santini R, et al. An antibiotic selection marker for nematode transgenesis. Nat Methods. 2010;7(9):721-723.\|[2]Volarevic M, et al. A novel G418 conjugate results in targeted selection of genetically protected hepatocytes without bystander toxicity. Bioconjug Chem. 2007;18(6):1965-1971.\|[3]Kwon KM, et al. Disialyl GD2 ganglioside suppresses ICAM-1-mediated invasiveness in human breast cancer MDA-MB231 cells. Int J Biol Sci. 2017;13(3):265-275. Published 2017 Feb 12.\|[4]Davies J, et al. A new selective agent for eukaryotic cloning vectors. Am J Trop Med Hyg. 1980;29(5 Suppl):1089-1092. Adv Healthc Mater. 2025 Mar 4:e2404501.\|Adv Sci (Weinh). 2025 Feb 11:e2404961.\|Am J Cancer Res. 2021 May 15;11(5):2062-2080.\|BMC Complement Med Ther. 2024 Nov 16;24(1):400.\|Cancer Commun (Lond). 2022 Nov 9.\|Cancer Res. 2023 Feb 6;CAN-22-3169.\|Cell Death Differ. 2020 Jun;27(6):1981-1997.\|Cell Death Dis. 2020 Jun 4;11(6):420.\|Cell Death Dis. 2019 May 28;10(6):413.\|Cell Rep. 2020 Oct 20;33(3):108287.\|Cell Rep. 2021 Mar 30;34(13):108906.\|Cell Rep. 2021 Sep 21;36(12):109739.\|Cell Rep. 2022 Oct 25;41(4):111561.\|Chemosphere. 2024 Sep 24:143350.\|Emerg Microbes Infect. 2023 Sep 19;2261556.\|Environ Toxicol. 2024 Jul 2.\|Eur J Pharmacol. 2025 Feb 22:177418.\|Hum Cell. 2022 Jul 6.\|J Agric Food Chem. 2022 Apr 6;70(13):3989-3999.\|J Biol Chem. 2023 Mar 17;104621.\|J Cell Mol Med. 2023 Mar 13.\|J Genet Genomics. 2021 Mar 30.\|Life Sci. 2024 Jun 1:346:122626.\|Med Oncol. 2021 Nov 10;39(1):10.\|Mol Cell. 2023 Nov 20:S1097-2765(23)00914-0.\|Nature. 2023 Jun;618(7966):862-870.\|Oxid Med Cell Longev. 2022 Jan 28;2022:8168988.\|Patent. US20240299557A1.\|Protein Cell. 2025 Feb 18:pwaf014.\|Research Square Preprint. 2020 Jun.\|Research Square Preprint. 2021 Nov.\|Research Square Print. 2023 Feb 21.\|Sci Adv. 2024 Aug 16;10(33):eado1533.\|Theranostics. 2022 Jan 1;12(3):1187-1203.\|Transl Cancer Res. 2023 Jan 23; 12(1):150-162.\|Acta Pharmacol Sin. 2023 May 16.\|Cell Mol Biol Lett. 2024 Feb 17;29(1):26.\|FASEB J. 2023 Nov;37(11):e23195.\|Research Square Preprint. 2023 Jul 11.\|SSRN. 2024 Jun 19.
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ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Geneticin sulfate,Antibiotic G-418 sulfate
Shipping Condition	Room temperature
Available
Manufacturer - Type	Natural Products
Manufacturer - Targets	Antibiotic; Bacterial
Shipping Temperature	Room Temperature
Storage Conditions	4°C (Powder, stored under nitrogen, away from moisture)
Molecular Weight	692.71
Product Description	G-418 disulfate (Geneticin sulfate), is an aminoglycoside antibiotic, inhibits protein synthesis in eukaryotes and prokaryotes. G-418 disulfate is commonly used as a selective agent for eukaryotic cells[1].
Manufacturer - Research Area	Infection
Solubility	H2O: 125 mg/mL (ultrasonic)
Manufacturer - Pathway	Anti-infection
Isoform	Aminoglycoside
Clinical information	No Development Reported

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HY-17561-500mg-safety-datasheet.pdf