L-Ascorbic acid (sodium)

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Menge 1g
ArtNr HY-B0166A-1g
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
(+)-Sodium L-ascorbate, Vitamin C sodium salt, Sodium L-ascorbate
CAS No.
134-03-2
Purity
>98%
MW
198.11
Formula
C6H7NaO6
Solubility
H2O: >= 41 mg/mL
Biological Description
L-Ascorbic acid (sodium) is a more bioavailable form of vitamin C that is an antioxidant agent.
IC50 & Target:
In Vitro: The conditioned medium for B16F10 cells significantly inhibits cell apoptosis induced by sodium L-ascorbate (10 mM), and the effective ingredients in the medium show a relative molecular mass below 5, 000[2].
In Vivo: Tg rats treated with sodium L-ascorbate show a higher incidence of carcinoma (29.6%), compared to those without sodium L-ascorbate (15.4%). Independent of the sodium L-ascorbate treatment, transgenic rats exhibit various kinds of malignant tumors in various organs[3]. After 12 weeks of PEITC-treatment, both simple hyperplasia and papillary or nodular (PN) hyperplasia have developed in all animals, but the majority of these lesions have disappeared at week 48, irrespective of the sodium L-ascorbate-treatment. The same lesions after 24 weeks of PEITC-treatment have progressed to dysplasia and carcinoma, in a small number of cases by week 48, but enhancement by the sodium L-ascorbate-treatment is evident only with simple hyperplasias and PN hyperplasias in rats[4].
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Sicherheitsdatenblatt

HY-B0166A-1g.pdf

Menge: 1g
Lieferbar: In stock
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