Lithocholic acid

Hersteller MedChem Express
Kategorie
Typ Inhibitors
Specific against other
Clon N/A
Menge 5g
ArtNr HY-B0172-5g
Eclass 6.1 30220300
Eclass 9.0 32160605
Lieferbar
Synonyms
3alpha-Hydroxy-5beta-cholanic acid
CAS No.
434-13-9
Purity
>98%
MW
3765726
Formula
C24H40O3
Solubility
10 mM in DMSO
Biological Description
Lithocholic acid is a toxic secondary bile acid, causes intrahepatic cholestasis, has tumor-promoting activity.
Target: Others
Lithocholic acid has been used in a study to assess cholestasis and its action on several organs and tissues in rats. It has also been used in a study to investigate the regulation of hepatic phospholipid and bile acid homeostasis through SMAD3 activation by TGFbeta. It has been implicated in human and experimental animal carcinogenesis. Preliminary in vitro research suggests that LCA selectively kills neuroblastoma cells, while sparing normal neuronal cells and is cytotoxic to numerous other malignant cell types at physiologically relevant concentrations.




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Sicherheitsdatenblatt

HY-B0172-5g.pdf

Menge: 5g
Lieferbar: In stock
Listenpreis: 143,21 €
Rabatt: -10,0%
Preis: 128,89 €
Sie sparen: 14,32 €
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