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Lithocholic acid

Lithocholic acid

Manufacturer	MedChem Express
Category	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Brain Cancer Nervous System Cancer
Type	Inhibitors
Specific against	other
Clone	N/A
Amount	5 g
Item no.	HY-B0172-5g
Targets	Autophagy; Endogenous Metabolite; Apoptosis
CASRN	434-13-9
eClass 6.1	30220300
eClass 9.0	32160605
Available
Product Description	Lithocholic acid is a toxic secondary bile acid that can promote intrahepatic cholestasis and promote tumorigenesis. Lithocholic acid is also a FXR antagonist and a PXR/SXR agonist[1][2][3][4][5].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	Metabolism-sugar/lipid metabolism
MolecularWeight	376.57
Clinical_Information	No Development Reported
Manufacturers Research_Area	Cancer; Metabolic Disease
Solubility	DMSO : 250 mg/mL (ultrasonic)\|Ethanol : 10 mg/mL (ultrasonic; warming; heat to 60°C)\|H2O : 0.99 mg/mL (ultrasonic; warming; adjust pH to 11 with NaOH; heat to 60°C)
Manufacturers Target	Apoptosis; Autophagy; Endogenous Metabolite; FXR
Isoform	Human Endogenous Metabolite; Microbial Metabolite
Pathway	Apoptosis; Autophagy; Metabolic Enzyme/Protease
Manufacturers Product type	Natural Products

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HY-B0172-5g-safety-datasheet.pdf