« Zurück
Home /
Thiabendazole

Thiabendazole

ArtNr	HY-B0263-10mM
Hersteller	MedChem Express
CAS-Nr.	148-79-8
Menge	10mM/1mL
Quantity options	10mM/1mL 1 g 500 mg 5 g
Kategorie	Oncology Inhibitors & Compound Libraries Small Molecules By Organ Bladder Cancer
Typ	Inhibitors
Clon	N/A
Specific against	other
Purity	99.88
Formula	C10H7N3S
Citations	[1]Cha, H.J., et al., Evolutionarily repurposed networks reveal the well-known antifungal drug thiabendazole to be a novel vascular disrupting agent. PLoS Biol, 2012. 10(8): p. e1001379.<br/>[2]Zhang, J., et al., Thiabendazole, a well-known antifungal drug, exhibits anti-metastatic melanoma B16F10 activity via inhibiting VEGF expression and inducing apoptosis. Pharmazie, 2013. 68(12): p. 962-8.<br/>[3]Budetić M, et al. Review of Characteristics and Analytical Methods for Determination of Thiabendazole. Molecules. 2023 May 6;28(9):3926. <br/>[4]Park J, et al. Developmental defects induced by thiabendazole are mediated via apoptosis, oxidative stress and alteration in PI3K/Akt and MAPK pathways in zebrafish. Environ Int. 2023 Jun;176:107973. <br/>[5]Elgebaly SA, et al. Thiabendazole-induced suppression of renal damage in a murine model of autoimmune disease. Am J Pathol. 1984 May;115(2):204-11. <br/>[6]Motwadie ME, et al. Modulation of immune functions, inflammatory response, and cytokine production following long-term oral exposure to three food additives; thiabendazole, monosodium glutamate, and brilliant blue in rats. Int Immunopharmacol. 2021 Sep;98:107902.
Smiles	C1(C2=CSC=N2)=NC3=CC=CC=C3N1
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Alias	Tiabendazole; 2-(4-Thiazolyl)benzimidazole
Lieferbar
Product Description	Thiabendazole is an orally available benzimidazole fungicide with repellent and anticancer activities. Thiabendazole can result in developmental malformations. Thiabendazole can be used for modeling[1][2][3][4][5].
StorageTemperature	-20°C, 3 years; 4°C, 2 years (Powder)
Shipping	Room Temperature
Manufacturers Applications	COVID-19-immunoregulation
MolecularWeight	201.25
Clinical Information	Launched
Manufacturers Research Area	Cancer; Infection; Inflammation/Immunology; Cardiovascular Disease
Solubility	DMSO : 50 mg/mL (ultrasonic)\|H2O : < 0.1 mg/mL (ultrasonic)
Target	Caspase; CDK; Interleukin Related; MDM-2/p53; Mitochondrial Metabolism; Parasite; VEGFR
Manufacturers Target	Caspase; CDK; Interleukin Related; MDM-2/p53; Mitochondrial Metabolism; Parasite; VEGFR
Isoform	Caspase 3; Caspase 9; CDK1; CDK2; IL-1; IL-10; IL-13; IL-6
Manufacturers Pathway	Anti-infection; Apoptosis; Cell Cycle/DNA Damage; Immunology/Inflammation; Metabolic Enzyme/Protease; Protein Tyrosine Kinase/RTK
Manufacturers Product type	Reference compound

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkdatenblatt anfordern

HY-B0263-10mM-safety-datasheet.pdf