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Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein (MHC-HE009B)

ArtNr MHC-HE009B-100UG
Hersteller KactusBio
Menge 100 ug
Quantity options 100 ug 500 ug
Kategorie
Format Liquid
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS, Avi
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Dry ice Yes
Sequence Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide
NCBI A0A140T913(HLA-A*02:01),P61769(B2M),KLIIVGAIGV
Alias MHC,RAB7B
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV)
Manufacturer - Conjugate / Tag
C-His-Avi
Shipping Temperature
Shipped with dry ice.
Storage Conditions
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Description
Recombinant Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide.
Background
Rab proteins are key-regulators of intracellular membrane trafficking. Rab7b is a recently identified Rab protein that may downregulate TLR4 and TLR9-mediated inflammatory responses. Rab7b, believed to have similar function as Rab7, controls however vesicular trafficking from endosomes to the TGN. It is localized to late endosomes/lysosomes as well as the TGN. Rab7b interferes with enzymes delivery to lysosomes and with the retrograde Shiga toxin transport to the Golgi.
Endotoxin
Less than 1 EU per μg by the LAL method.
Formulation
Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Biotinylated
yes

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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