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Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein (MHC-HE009B)

Biotinylated Human HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein (MHC-HE009B)

Item no.	MHC-HE009B-100UG
Manufacturer	KactusBio
Amount	100 ug
Quantity options	100 ug 500 ug
Category	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Cell Biology Adenocarcinoma Cytoskeleton Myelofibrosis Mesothelioma Astrocytoma By Organ Heart & Blood Cancer small GTPases Rab Subfamily
Format	Liquid
Specific against	Human (Homo sapiens)
Host	E.coli
Conjugate/Tag	HIS, Avi
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Dry ice	Yes
Sequence	Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide
NCBI	A0A140T913(HLA-A*02:01),P61769(B2M),KLIIVGAIGV
Alias	MHC,RAB7B
Shipping Condition	Dry ice
Available
Manufacturer - Type	Recombinant Protein
Manufacturer - Targets	HLA-A*02:01&B2M&RAB7B (KLIIVGAIGV)
Manufacturer - Conjugate / Tag	C-His-Avi
Shipping Temperature	Shipped with dry ice.
Storage Conditions	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight	The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Description	Recombinant Biotinylated Human HLA-A02:01&B2M&RAB7B (KLIIVGAIGV) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A02:01), Ile21-Met119(B2M) and KLIIVGAIGV peptide.
Background	Rab proteins are key-regulators of intracellular membrane trafficking. Rab7b is a recently identified Rab protein that may downregulate TLR4 and TLR9-mediated inflammatory responses. Rab7b, believed to have similar function as Rab7, controls however vesicular trafficking from endosomes to the TGN. It is localized to late endosomes/lysosomes as well as the TGN. Rab7b interferes with enzymes delivery to lysosomes and with the retrograde Shiga toxin transport to the Golgi.
Endotoxin	Less than 1 EU per μg by the LAL method.
Formulation	Supplied as 0.22 μm filtered solution in PBS (pH 7.4).
Biotinylated	yes

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

MHC-HE009B-100UG-datasheet.pdf

MHC-HE009B-100UG-safety-datasheet.pdf