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Human HLA-A*02:01&B2M&AFP (FMNKFIYEl) Monomer Protein (MHC-HE017)

ArtNr MHC-HE017-500UG
Hersteller KactusBio
Menge 500 ug
Quantity options 100 ug 500 ug
Kategorie
Format Liquid
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS, Avi
Purity > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Dry ice Yes
Sequence Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and FMNKFIYEl peptide
NCBI A0A140T913(HLA-A*02:01),P61769(B2M),FMNKFIYEl
Alias Alpha-fetoprotein,Alpha-1-fetoprotein,Alpha-feto,AFP,HPAFP,AFPD,FETA
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Targets
HLA-A*02:01&B2M&AFP (FMNKFIYEl)
Manufacturer - Conjugate / Tag
C-His-Avi
Shipping Temperature
Shipped with dry ice.
Storage Conditions
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Molecular Weight
The protein has a predicted MW of 35.6 kDa (HLA-A*02:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Description
Recombinant Human HLA-A*02:01&B2M&AFP (FMNKFIYEl) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and FMNKFIYEl peptide.
Background
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple tissue types that were negative for either expressed proteins.CAR T-cell immunotherapy targeting intracellular/secreted solid tumor antigens can elicit a potent antitumor response.
Endotoxin
Less than 1 EU per μg by the LAL method.
Formulation
Supplied as 0.22 μm filtered solution in 20mM Tris, 200mM NaCl (pH 8.0).
Biotinylated
no

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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