Balapiravir (R1626, Ro 4588161)

InvivoChem Cat #:V2064CAS #:690270-29-2 Purity >=98%

Description: Balapiravir (also known as R1626 and Ro 4588161) is the tri-isobutyl ester prodrug of R1479 which is a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase. Balapiravir was developed to increase bioavailability and improve antiviral activity.

References: J Virol. 2014 Feb; 88(3):1740-1747.

Related CAS#: 690270-65-6 (HCl)

-20C for 3 years in powder form

Synonym: R1626; R-1626; R 1626; RO4588161; RO-4588161; RO 4588161
Chemical Name: (2R, 3S, 4R, 5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-azido-2-((isobutyryloxy)methyl)tetrahydrofuran-3, 4-diyl bis(2-methylpropanoate)
InChi Key: VKXWOLCNTHXCLF-DXEZIKHYSA-N
InChi Code: InChI=1S/C21H30N6O8/c1-10(2)17(28)32-9-21(25-26-23)15(34-19(30)12(5)6)14(33-18(29)11(3)4)16(35-21)27-8-7-13(22)24-20(27)31/h7-8, 10-12, 14-16H, 9H2, 1-6H3, (H2, 22, 24, 31)/t14-, 15+, 16-, 21-/m1/s1
SMILES Code: CC(C(O[CH]([CH]([C]1(COC(C(C)C)=O)N=[N+]=[N-])OC(C(C)C)=O)[CH](O1)N(C=CC(N)=N2)C2=O)=O)C