Valbenazine

ArtNr	V2960-50mg
Hersteller	InvivoChem LLC
CAS-Nr.	1025504-45-3
Menge	50 mg
Quantity options	100 mg 10 mg 250 mg 25 mg 500 mg 5 mg
Kategorie	Reagents & Chemicals Molecules
Typ	Biochemicals
Specific against	other
ECLASS 10.1	32160490
ECLASS 11.0	32160490
UNSPSC	12000000
Lieferbar
Description	InvivoChem Cat #:V2960CAS #:1025504-45-3 Purity >=98% Description: Valbenazine (formerly also known as NBI-98854 and MT-5199; trade name: Ingrezza) is a potent and selective inhibitor of VMAT2 (vesicular monoamine transporter 2). As of 2017, it has been approved by FDA to treat adults with tardive dyskinesia. Valbenazine is a prodrug of the (+)-alpha isomer of tetrabenazine for tardive syndrome therapy. It is effective in regulating the levels of dopamine release during nerve communication, while at the same time having minimal impact on the other monoamines. Valbenazine is used to treat tardive dyskinesia in adults. Tardive dyskinesia is a neurological disorder characterized by involuntary movements. The clinical trials that led to FDA approval of valbenzazine were 6 weeks in duration. An industry-sponsored study has studied the use of valbenzazine for up to 48 weeks, in which it was found to be safe and effective for maintaining short-term (6 week) improvements in tardive dyskinesia. Description: References: Expert Opin Investig Drugs. 2015 Jun; 24(6):737-42. References: Related CAS#:1639208-54-0 (tosylate); 1639208-51-7 (2HCl)
Molecular Weight (MW)	418.57
Formula	C24H38N2O4
CAS No.	1025504-45-3 (free base);
Storage	-20C for 3 years in powder form
	-80C for 2 years in solvent
Solubility (In vitro)	DMSO: 10 mM
	Water: < 1 mg/mL
	Ethanol: < 1 mg/mL
SMILES	N[CH](C(C)C)C(O[CH]1[CH](CC(C)C)CN2CCC3=CC(OC)=C(OC)C=C3[C]2([H])C1)=O
Synonyms	Valbenazine; NBI-98854; NBI 98854; NBI98854; MT-5199; MT 5199; MT5199; trade name: Ingrezza

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkt-Datenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 50 mg

lieferbar

Lieferung vsl. bis 04.09.2025