Iproniazid

Description: Iproniazid (brand/other names of Marsilid, Rivivol, Euphozid, Iprazid, Ipronid, Ipronin) is a non-selective, and irreversible monoamine oxidase inhibitor (MAOI). Monoamine oxidases is a family of FAD-containing enzymes and is an important target for antidepressant drugs. Iproniazid has been used as an antidepressive agent in many countries. It is a xenobiotic that was originally designed to treat tuberculosis, but was later found to act most prominently as an antidepressant drug. The medical use of iproniazid was discontinued in most of the world due to its hepatotoxicity, but remained in use in France until fairly recently.

References: Molecules. 2014 Nov 14; 19(11):18620-31; https://en.wikipedia.org/wiki/Iproniazid