FAAH-IN-2

Description: FAAH-IN-2 is a novel and potent FAAH (fatty acid amide hydrolase) inhibitor extracted from Patent WO/2008/100977A2. It is also named as O-Desmorpholinopropyl Gefitinib and is a metabolite of gefitinib, which is an EGFR inhibitor. FAAHs (also known as EC 3.5.1.99, oleamide hydrolase, anandamide amidohydrolase) are a family of enzymes that belong to serine hydrolases. In humans, the family is represented by FAAH 1 and 2. It was first shown to break down anandamide in 1993. In humans, it is encoded by the gene FAAH. FAAH-IN-2 has the chemical name of 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-ol; 4-((3-Chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-ol; FAAH-IN-2; O-Desmorpholinopropyl Gefitinib; JLVTVCRXFMLUIF-UHFFFAOYSA-N.

References: WO/2008/100977A2

InChi Key: JLVTVCRXFMLUIF-UHFFFAOYSA-N

InChi Code: InChI=1S/C15H11ClFN3O2/c1-22-14-6-12-9(5-13(14)21)15(19-7-18-12)20-8-2-3-11(17)10(16)4-8/h2-7, 21H, 1H3, (H, 18, 19, 20)