TAFLUPROST

InvivoChem Cat #:V4395CAS #:209860-87-7 Purity >=98%

Description: Tafluprost ( also known as MK2452 and AFP-168) is a prostaglandin (PG) analog used as an anti-glaucoma drug. Tafluprost is used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension. It reduces intraocular pressure by increasing the outflow of aqueous fluid from the eyes.

References: Adv Ther, 2014. 31(4): p. 461-71.; J Ocul Pharmacol Ther, 2014. 30(4): p. 340-5.

Related CAS#: 209860-88-8 (Tafluprost acid); 157283-68-6 (Travoprost)

-20C for 3 years in powder form

Synonym: AFP-168; AFP-168; AFP-168; MK-2452; MK2452; MK 2452; Saflutan, Taflotan, Tapros, Zioptan
IUPAC/Chemical Name: isopropyl (5Z)-7-{(1R, 2R, 3R, 5S)-2-[(1E)-3, 3-difluoro-4-phenoxybut-1-en-1-yl]-3, 5-dihydroxycyclopentyl}hept-5-enoate
InChi Key: WSNODXPBBALQOF-VEJSHDCNSA-N
InChi Code: InChI=1S/C25H34F2O5/c1-18(2)32-24(30)13-9-4-3-8-12-20-21(23(29)16-22(20)28)14-15-25(26, 27)17-31-19-10-6-5-7-11-19/h3, 5-8, 10-11, 14-15, 18, 20-23, 28-29H, 4, 9, 12-13, 16-17H2, 1-2H3/b8-3-, 15-14+/t20-, 21-, 22+, 23-/m1/s1
SMILES Code: O=C(OC(C)C)CCC/C=C\C[CH]1[CH](/C=C/C(F)(F)COC2=CC=CC=C2)[CH](O)C[CH]1O