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imiglitazar

ArtNr V4599-100mg
Hersteller InvivoChem LLC
CAS-Nr. 250601-04-8
Menge 100 mg
Quantity options 10 mg 250 mg 25 mg 50 mg
Kategorie
Typ Biochemicals
Specific against other
ECLASS 10.1 32160490
ECLASS 11.0 32160490
UNSPSC 12000000
Lieferbar
Description
InvivoChem Cat #:V4599CAS #:250601-04-8Purity >=98%

Description: Imiglitazar (also known as TAK559; proposed tradename Pargluva) is a novel, potent and dual human peroxisome proliferator-activated receptor PPARalpha and PPARgamma1 agonist with EC50 values of 67 and 31 nM and with hypoglycemic activity. Muraglitazar had completed phase III clinical trials, however in May, 2006 Bristol-Myers Squibb announced that it had discontinued further development.. Data on muraglitazar isrelatively sparse due to the recent introduction of this agent.

Description: Imiglitazar (also known as TAK559; proposed tradename Pargluva) is a novel, potent and dual human peroxisome proliferator-activated receptor PPARalpha and PPARgamma1 agonist with EC50 values of 67 and 31 nM and with hypoglycemic activity. Muraglitazar had completed phase III clinical trials, however in May, 2006 Bristol-Myers Squibb announced that it had discontinued further development.. Data on muraglitazar isrelatively sparse due to the recent introduction of this agent.Description50

References: Eur J Pharmacol. 2004 Jul 8; 495(1):17-26.

References: Eur J Pharmacol. 2004 Jul 8; 495(1):17-26.References: Eur J Pharmacol. 2004 Jul 8; 495(1):17-26.References


Imiglitazar

Name: Imiglitazar
CAS#: 250601-04-8
Chemical Formula: C28H26N2O5
Exact Mass: 470.18417
Molecular Weight: 470.52
Elemental Analysis: C, 71.47; H, 5.57; N, 5.95; O, 17.00
Storage
-20C for 3 years in powder form
-80C for 2 years in solvent
Technical Information
Synonym: TAK 559; TAK-559; TAK559.
IUPAC/Chemical Name: Benzenebutanoic acid, gamma-(((4-((5-methyl-2-phenyl-4-oxazolyl)methoxy)phenyl)methoxy)imino)-, (gammaE)-
InChi Key: ULVDFHLHKNJICZ-QCWLDUFUSA-N
InChi Code: InChI=1S/C28H26N2O5/c1-20-26(29-28(35-20)23-10-6-3-7-11-23)19-33-24-14-12-21(13-15-24)18-34-30-25(16-17-27(31)32)22-8-4-2-5-9-22/h2-15H, 16-19H2, 1H3, (H, 31, 32)/b30-25+
SMILES Code: O=C(O)CC/C(C1=CC=CC=C1)=N\OCC2=CC=C(OCC3=C(C)OC(C4=CC=CC=C4)=N3)C=C2

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 mg
Lieferbar: In stock
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