limaprost

InvivoChem Cat #:V4638CAS #:74397-12-9Purity >=98%

Description: Limaprost (formerly also known as ONO 1206 and OP1206) is, an alprostadil (prostaglandin E1) analogue, is a novel and potent vasodilator that increases blood flow and inhibits platelet aggregation. It is an orally available prostaglandin E1 analog with structural modifications intended to prolong half-life and improve potency. Limaprost reduces motor disturbances by increasing the production of insulin-like growth factor I in rats subjected to spinal cord injury.

References: Arch Int Pharmacodyn Ther, 1980. 247(1): p. 89-102.;

Related CAS : 74397-12-9; 88852-12-4 (Limaprost alfadex); 10016-20-3 (Alfadex)

-20C for 3 years in powder form

Synonym: ONO 1206; ONO 1206; ONO 1206; OP 1206; Limaprost; 17alpha, 20-dimethyl-delta2-Prostaglandin E1; 17alpha, 20-dimethyl-delta2-PGE1; OP1206; OP-1206.
IUPAC/Chemical Name: (2E, 11-alpha, 13E, 15S, 17S)-11, 15-Dihydroxy-17, 20-dimethyl-9-oxoprosta-2, 13-dien-1-oic acid
InChi Key: OJZYRQPMEIEQFC-UAWLTFRCSA-N
InChi Code: InChI=1S/C22H36O5/c1-3-4-9-16(2)14-17(23)12-13-19-18(20(24)15-21(19)25)10-7-5-6-8-11-22(26)27/h8, 11-13, 16-19, 21, 23, 25H, 3-7, 9-10, 14-15H2, 1-2H3, (H, 26, 27)/b11-8+, 13-12+/t16-, 17+, 18+, 19+, 21+/m0/s1
SMILES Code: O=C(O)/C=C/CCCC[CH]1C(C[CH](O)[CH]1/C=C/[CH](O)C[CH](C)CCCC)=O