Vergleich

Recombinant human CCL2/MCP-1 protein

ArtNr NKM-ATGP4067-100ug
Hersteller NKMAX
Menge 100 ug
Quantity options 100 ug 10 ug 20 ug 250 ug 500 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag HIS
Purity > 90% by SDS - PAGE
Sequence QPDAINAPVT CCYNFTNRKI SVQRLASYRR ITSSKCPKEA VIFKTIVAKE ICADPKQKWV QDSMDHLDKQ TQTPKT<HHHH HH>
Citations Foresti ML, Arisi GM, et al. (2009). J Neuroinflammation. 6:40.
Semple BD, Bye N, et al. (2010). J Cereb Blood Flow Metab. 30:769-782.
NCBI NP_002973.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias C-C motif chemokine 2, CCL2, GDCF-2, HSMCR30, HC11, JE, MCAF, MCP-1, MCP1, Scya2, Sigje, SMC-CF, Immediate-early serum-responsive protein JE, Monocyte chemoattractant protein 1, Small-inducible cytokine A2
Similar products ATGP4067-10ug, ATGP4067-20ug, ATGP4067-50ug, ATGP4067-100ug, ATGP4067-250ug, ATGP4067-500ug, ATGP4067-1mg, ATGP4067-10, ATGP4067-20, ATGP4067-50, ATGP4067-100, ATGP4067-250, ATGP4067-500, ATGP4067-1
Lieferbar
Manufacturer - Type
Proteins
Manufacturer - Applications
SDS-PAGE, Bioactivity
Manufacturer - Category
Recombinant Protein
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
9.5kDa (82aa)
Description
CCL2(Chemokine ligand 2), as known as MCP-1(monocyte chemotactic protein-1), is a small cytokine belonging to the CC chemokine family. This protein recruits monocytes, memory T cells, and dendritic cells to sites of tissue injury and infection. It binds to chemokine receptors CCR2 and CCR4. It also induces enzyme and cytokine release by monocytes, NK cells and lymphocytes, and histamine release by basophils, primarily due to interaction with CCR2 receptors on these cells. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. Recombinant human CCL2/JE/MCP-1, fused to His-tag at C-terminus, was expressed in HEK293 and purified by using conventional chromatography techniques.
Concentration
0.25mg/ml (determined by Absorbance at 280nm)
Formulation
Liquid. In Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Antigen Species
Human
Gene Category
Immunology, Hormones & Cytokines
Domain
24-99aa
Endotoxin
< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment Only
Measured its ability to chemoattract using THP-1 human acute monocytic leukemia cells. The ED50 range ≤ 30 ng/ml.
Predicted nterm
Gln 24
Species of Protein
Human
Manufacturer - Search Terms
ATGP4067-10ug, ATGP4067-20ug, ATGP4067-50ug, ATGP4067-100ug, ATGP4067-250ug, ATGP4067-500ug, ATGP4067-1mg, ATGP4067-10, ATGP4067-20, ATGP4067-50, ATGP4067-100, ATGP4067-250, ATGP4067-500, ATGP4067-1
Manufacturer - Alternative Names
SMC-CF, Small inducible cytokine subfamily A member 2, Small inducible cytokine A2, SCYA2, Monocyte secretory protein JE, Monocyte chemotactic protein 1 homologous to mouse Sig-je, Monocyte chemotactic and activating factor, MGC9434, MCP-1, MCP1, MCAF, HC11, GDCF-2, C-C motif chemokine ligand 2

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
lieferbar

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen