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Human Leptin/OB antibody

ArtNr NKM-ATGA0460-50ul
Hersteller NKMAX
Menge 50 ul
Quantity options 100 ul 50 ul
Kategorie
Typ Antibody Monoclonal
Format Liquid
Applikationen WB, ICC, ELISA
Clon AT7E10
Specific against Human (Homo sapiens)
Host Mouse
Isotype IgG2b Kappa
Konjugat/Tag Unconjugated
Citations Anini Y., et al. (2003) Diabetes. 52(2): 252-259.
Jeong KJ., et al. (1999) Appl Environ Microbiol. 65(7): 3027-32.
Hyogo H., et al. (2002) J. Biol. Chem. 277(37): 34117-34124.
NCBI NP_000221
ECLASS 10.1 42030590
ECLASS 11.0 42030590
UNSPSC 12352203
Alias LEP,OB,OBS,Leptin,Obesity factor,Obese protein,Leptin,Leptin Murine Obesity Homolog,Leptin Precursor Obesity Factor,Obesity,Obesity homolog mouse,Obesity Murine Homolog Leptin
Similar products Leptin, OB, ATGA0460-10ug, ATGA0460-20ug, ATGA0460-50ug, ATGA0460-100ug, ATGA0460-250ug, ATGA0460-500ug, ATGA0460-1mg, ATGA0460-10, ATGA0460-20, ATGA0460-50, ATGA0460-100, ATGA0460-250, ATGA0460-500, ATGA0460-1
Lieferbar
Manufacturer - Type
Monoclonal Antibody
Manufacturer - Applications
ELISA, WB, ICC/IF
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Description
Human leptin is a 16-kDa nonglycosylated hormone that is produced in mature adipocytes. Leptin acts primarily in the hypothalamus to reduce food intake and body weight. In ob/ob mice, the gene encoding leptin is mutated, resulting in morbid obesity and associated abnormalities, including hyperphagia, hypothermia, diabetes and infertility. The function of leptin in regulating appetite and metabolism, as well as the possibility of using leptin as a therapeutic agent, are currently under intense investigation.
Concentration
1mg/ml (determined by BCA assay)
Formulation
Liquid in. Phosphate-Buffered Saline (pH 7.4) with 0.02% Sodium Azide, 10% glycerol
Immunogen
Recombinant human Leptin (22-167aa) purified from E. coli
Ab Usage
The antibody has been tested by ELISA, Western blot and ICC/IF analysis to assure specificity and reactivity. Since application varies, however, each investigation should be titrated by the reagent to obtain optimal results.
Antigen Species
Human
Clonality
Monoclonal
Ab Purification Comment
By protein-A affinity chromatography
Gene Category
Signal Transduction
Manufacturer - Search Terms
Leptin, OB, ATGA0460-10ug, ATGA0460-20ug, ATGA0460-50ug, ATGA0460-100ug, ATGA0460-250ug, ATGA0460-500ug, ATGA0460-1mg, ATGA0460-10, ATGA0460-20, ATGA0460-50, ATGA0460-100, ATGA0460-250, ATGA0460-500, ATGA0460-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ul
Lieferbar: In stock
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