Recombinant human CD40 Ligand/CD40LG protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

CD40 ligand, also known as CD40LG, is a member of the TNF superfamily and is expressed on activated T cells. CD40LG is expressed as a soluble cytokine as well as a homotrimeric type II transmembrane protein. It has been reported to be important for B cell costimulation following binding of its receptor, CD40. Mutations in the gene encoding for CD154 are implicated in hyper-IgM immunodeficiency syndrome type 1. Recombinant human CD40LG protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 1mM DTT, 40% glycerol, 0.2M NaCl

Immunology

< 1 EU per 1ug of protein (determined by LAL method)

CD40 Ligand, TNFSF5, CD40 ligand, CD154, CD40L, gp39, hCD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, ATGP1017-10ug, ATGP1017-20ug, ATGP1017-50ug, ATGP1017-100ug, ATGP1017-250ug, ATGP1017-500ug, ATGP1017-1mg, ATGP1017-10, ATGP1017-20, ATGP1017-50, ATGP1017-100, ATGP1017-250, ATGP1017-500, ATGP1017-1