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Recombinant human SOCS-3 protein

ArtNr NKM-ATGP2589-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMVT HSKFPAAGMS RPLDTSLRLK TFSSKSEYQL VVNAVRKLQE SGFYWSAVTG GEANLLLSAE PAGTFLIRDS SDQRHFFTLS VKTQSGTKNL RIQCEGGSFS LQSDPRSTQP VPRFDCVLKL VHHYMPPPGA PSFPSPPTEP SSEVPEQPSA QPLPGSPPRR AYYIYSGGEK IPLVLSRPLS SNVATLQHLC RK
Citations McKay BR, Ogborn DI, et al. (2013). Am J Physiol Cell Physiol. 304(8):C717-28.
Molavi O, Wang P, et al. (2013). Br J Haematol. 161(3):348-56.
NCBI NP_003946
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Suppressor of cytokine signaling 3,CIS3,SSI3,ATOD4,Cish3,SSI-3,SOCS-3,MGC71791
Similar products SOCS-3, SOCS3, CIS3, SSI3, Suppressor of cytokine signaling 3, ATOD4, Cish3, MGC71791, SSI-3, ATGP2589-10ug, ATGP2589-20ug, ATGP2589-50ug, ATGP2589-100ug, ATGP2589-250ug, ATGP2589-500ug, ATGP2589-1mg, ATGP2589-10, ATGP2589-20, ATGP2589-50, ATGP2589-100, ATGP2589-250, ATGP2589-500, ATGP2589-1
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Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
29 kDa (262aa)
Description
SOCS3 is a member of the STAT-induced STAT inhibitor (SSI), also known as suppressor of cytokine signaling (SOCS), family. SSI family members are cytokine-inducible negative regulators of cytokine signaling. The expression of SOCS3 is induced by various cytokines, including IL6, IL10, and interferon (IFN) -gamma. This protein can bind to JAK2 kinase, and inhibit the activity of JAK2 kinase. Studies of the mouse counterpart of this gene suggested the roles of this gene in the negative regulation of fetal liver hematopoiesis, and placental development. Recombinant human SOCS3 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% glycerol
Antigen Species
Human
Gene Category
Metabolism
Domain
1-225aa
Species of Protein
Human
Manufacturer - Search Terms
SOCS3, Suppressor of cytokine signaling 3, CIS3, SSI3, ATOD4, Cish3, SSI-3, SOCS-3, MGC71791, ATGP2589-10ug, ATGP2589-20ug, ATGP2589-50ug, ATGP2589-100ug, ATGP2589-250ug, ATGP2589-500ug, ATGP2589-1mg, ATGP2589-10, ATGP2589-20, ATGP2589-50, ATGP2589-100, ATGP2589-250, ATGP2589-500, ATGP2589-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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