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Recombinant human GAD1/GAD67 protein

ArtNr NKM-ATGP2642-50ug
Hersteller NKMAX
Menge 50 ug
Quantity options 10 ug 250 ug 50 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 85% by SDS-PAGE
Sequence <MGSSHHHHHH SSGLVPRGSH MGS>MASSTPS SSATSSNAGA DPNTTNLRPT TYDTWCGVAH GCTRKLGLKI CGFLQRTNSL EEKSRLVSAF KERQSSKNLL SCENSDRDAR FRRTETDFSN LFARDLLPAK NGEEQTVQFL LEVVDILLNY VRKTFDRSTK VLDFHHPHQL LEGMEGFNLE LSDHPESLEQ ILVDCRDTLK YGVRTGHPRF FNQLSTGLDI IGLAGEWLTS
Citations Chessler S.D., Lernmark A., et al. (2000) J. Biol. Chem. 275:5188-5192.
NCBI NP_038473.2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Glutamate decarboxylase 1 isoform GAD25,Glutamate decarboxylase 1 (brain,67kDa),CPSQ1,GAD,SCP
Similar products GAD1, GAD, GAD67, SCP, CPSQ1, Glutamate decarboxylase 1 (brain, 67kDa), Glutamate decarboxylase 1 isoform GAD25, ATGP2642-10ug, ATGP2642-20ug, ATGP2642-50ug, ATGP2642-100ug, ATGP2642-250ug, ATGP2642-500ug, ATGP2642-1mg, ATGP2642-10, ATGP2642-20, ATGP2642-50, ATGP2642-100, ATGP2642-250, ATGP2642-500, ATGP2642-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE, Denatured
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
27.7 kDa (247aa)
Description
GAD1 is one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. It is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This protien may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form. Recombinant human GAD1 protein, fused to His-tag at N-terminus, was expressed in E. coli.
Concentration
0.5mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M urea
Antigen Species
Human
Gene Category
Neuroscience
Domain
1-224aa
Species of Protein
Human
Manufacturer - Search Terms
GAD1, GAD67, Glutamate decarboxylase 1 isoform GAD25, Glutamate decarboxylase 1 (brain, 67kDa), CPSQ1, GAD, SCP, ATGP2642-10ug, ATGP2642-20ug, ATGP2642-50ug, ATGP2642-100ug, ATGP2642-250ug, ATGP2642-500ug, ATGP2642-1mg, ATGP2642-10, ATGP2642-20, ATGP2642-50, ATGP2642-100, ATGP2642-250, ATGP2642-500, ATGP2642-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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