ArtNr |
NKM-ATGP3572-50ug |
Hersteller |
NKMAX
|
Menge |
50 ug |
Quantity options |
10 ug
250 ug
50 ug
|
Kategorie |
|
Typ |
Proteins Recombinant |
Specific against |
other |
Konjugat/Tag |
HIS |
Purity |
> 90% by SDS - PAGE |
Sequence |
ADPEEELQMI QPEKLLLVTV GKTATLHCTV TSLLPVGPVL WFRGVGPGRE LIYNQKEGHF PRVTTVSDLT KRNNMDFSIR ISSITPADVG TYYCVKFRKG SPENVEFKSG PGTEMALGAK PSAPVVLGPA ARTTPEHTVS FTCESHGFSP RDITLKWFKN GNELSDFQTN VDPTGQSVAY SIRSTARVVL DPWDVRSQVI CEVAHVTLQG DPLRGTANLS EAIRVPPTLE VT |
Citations |
Nettleship JE., et al. (2013) BMC Struct Biol. 13:13. Brooke G., et al. (2004) J Immunol. 173:2562-2570 |
NCBI |
NP_061026 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Signal-regulatory protein gamma isoform 1, SIRPG, bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma |
Lieferbar |
|
Manufacturer - Applications |
SDS-PAGE |
Manufacturer - Conjugate / Tag |
hIgG-His-Tag |
Manufacturer - Host |
Baculovirus |
Storage Conditions |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Molecular Weight |
64.0kDa (574aa) 70-100kDa (SDS-PAGE under reducing conditions) |
Description |
SIRPG, also known as signal-regulatory protein gamma isoform 1, is a member of a closely related family of three cell surface receptors implicated in modulating immune/inflammatory responses. It is expressed on T lymphocytes where it appears to be involved in the integrin-independent adhesion of lymphocytes to antigen-presenting cells. Adhesion of human T cells to antigen-presenting cells through it interaction costimulates T-cell proliferation. Recombinant human SIRPG, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Concentration |
0.5mg/ml (determined by Absorbance at 280nm) |
Formulation |
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol. |
Antigen Species |
Human |
Gene Category |
Immunology, Adhesion & Movement |
Domain |
29-360aa |
Endotoxin |
< 1.0 EU per 1ug of protein (determined by LAL method) |
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