Item no. |
NKM-ATGP3572-50ug |
Manufacturer |
NKMAX
|
Amount |
50 ug |
Quantity options |
10 ug
250 ug
50 ug
|
Category |
|
Type |
Proteins Recombinant |
Specific against |
other |
Conjugate/Tag |
HIS |
Purity |
> 90% by SDS - PAGE |
Sequence |
ADPEEELQMI QPEKLLLVTV GKTATLHCTV TSLLPVGPVL WFRGVGPGRE LIYNQKEGHF PRVTTVSDLT KRNNMDFSIR ISSITPADVG TYYCVKFRKG SPENVEFKSG PGTEMALGAK PSAPVVLGPA ARTTPEHTVS FTCESHGFSP RDITLKWFKN GNELSDFQTN VDPTGQSVAY SIRSTARVVL DPWDVRSQVI CEVAHVTLQG DPLRGTANLS EAIRVPPTLE VT |
Citations |
Nettleship JE., et al. (2013) BMC Struct Biol. 13:13. Brooke G., et al. (2004) J Immunol. 173:2562-2570 |
NCBI |
NP_061026 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Signal-regulatory protein gamma isoform 1, SIRPG, bA77C3.1, CD172g, SIRP-B2, SIRPB2, SIRPgamma |
Available |
|
Manufacturer - Applications |
SDS-PAGE |
Manufacturer - Conjugate / Tag |
hIgG-His-Tag |
Manufacturer - Host |
Baculovirus |
Storage Conditions |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Molecular Weight |
64.0kDa (574aa) 70-100kDa (SDS-PAGE under reducing conditions) |
Description |
SIRPG, also known as signal-regulatory protein gamma isoform 1, is a member of a closely related family of three cell surface receptors implicated in modulating immune/inflammatory responses. It is expressed on T lymphocytes where it appears to be involved in the integrin-independent adhesion of lymphocytes to antigen-presenting cells. Adhesion of human T cells to antigen-presenting cells through it interaction costimulates T-cell proliferation. Recombinant human SIRPG, fused to hIgG-His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Concentration |
0.5mg/ml (determined by Absorbance at 280nm) |
Formulation |
Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol. |
Antigen Species |
Human |
Gene Category |
Immunology, Adhesion & Movement |
Domain |
29-360aa |
Endotoxin |
< 1.0 EU per 1ug of protein (determined by LAL method) |
Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.
All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.