Recombinant human Glycine N-methyltransferase/GNMT protein

Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.

Glycine N-methyltransferase, also known as GNMT, catalyzes the synthesis of N-methylglycine (sarcosine) from glycine using S-adenosylmethionine (AdoMet) as the methyl donor. This protein affects DNA methylation by regulating the ratio of S-adenosylmethionine to S-adenosylhomocystine and participates in the detoxification pathway in liver cells. Also it is reported that GNMT expression is diminished in human hepatocellular carcinoma (HCC). Recombinant human GNMT protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol

Enzymes & Proteases

< 1 EU per 1ug of protein (determined by LAL method)

Glycine N-methyltransferase, GNMT, Glycine N-methyltransferase, GNMT, Glycine N-methyltransferase, Glycine N-methyltransferase EC 2.1.1.20, Glycine N methyltransferase., GNM0901-10ug, GNM0901-20ug, GNM0901-50ug, GNM0901-100ug, GNM0901-250ug, GNM0901-500ug, GNM0901-1mg, GNM0901-10, GNM0901-20, GNM0901-50, GNM0901-100, GNM0901-250, GNM0901-500, GNM0901-1