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Rabbit antibody to P2RY1

Rabbit antibody to P2RY1

ArtNr	OSP00121W
Hersteller	Osenses
Menge	100ul
Kategorie	Neuroscience Neural Lineage Markers Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Guinea Pig
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	P2Y purinoceptor 1, P2Y1, Purinergic receptor, ATP receptor
Similar products	P2Y1, ATP receptor, Purinergic receptor, P2Y purinoceptor 1
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Also known	P2Y purinoceptor 1, P2Y1, Purinergic receptor, ATP receptor
Target	FUNCTION: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Repressed by the P2Y1 receptor-specific antagonists A3P5PS, A3P5P and A2P5P. These inhibit calcium ion mobilization and shape change in platelets. Subcellular location: Membrane; Multi-pass membrane protein.
Spcs X-react.	Human, guinea pig. Other species not yet tested but expected to work in rat.
Applications info	IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Shipping	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Leon C, et al. Gene 171:295-297(1996) 2. Zahedi R.P, et al. J. Proteome Res. 7:526-534(2008)
Limitation	For research use only
Immunogen	A synthetic peptide from the extracellular domain of human P2Y1 (P2RY1) conjugated to an immunogenic carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	http://www.uniprot.org/uniprot/P47900 http://www.uniprot.org/uniprot/P49651 http://www.uniprot.org/uniprot/P59902
Purity	Whole serum
Clonality	Polyclonal
Specificity	Specific for P2RY1.
Format	Lyophilised
Reconstitution	Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100ul

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