Comparison

Rabbit antibody to P2RY1

Item no. OSP00121W
Manufacturer Osenses
Amount 100ul
Category
Type Antibody Polyclonal
Applications WB, IHC
Specific against Human (Homo sapiens), Guinea Pig
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias P2Y purinoceptor 1, P2Y1, Purinergic receptor, ATP receptor
Similar products P2Y1, ATP receptor, Purinergic receptor, P2Y purinoceptor 1
Available
Also known
P2Y purinoceptor 1, P2Y1, Purinergic receptor, ATP receptor
Target
FUNCTION: Receptor for extracellular adenine nucleotides such as ATP and ADP. In platelets binding to ADP leads to mobilization of intracellular calcium ions via activation of phospholipase C, a change in platelet shape, and probably to platelet aggregation. Repressed by the P2Y1 receptor-specific antagonists A3P5PS, A3P5P and A2P5P. These inhibit calcium ion mobilization and shape change in platelets.
Subcellular location: Membrane; Multi-pass membrane protein.
Spcs X-react.
Human, guinea pig. Other species not yet tested but expected to work in rat.
Applications info
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Leon C, et al. Gene 171:295-297(1996)
2. Zahedi R.P, et al. J. Proteome Res. 7:526-534(2008)
Limitation
For research use only
Immunogen
A synthetic peptide from the extracellular domain of human P2Y1 (P2RY1) conjugated to an immunogenic carrier protein was used as the antigen.
Conjugate
Unconjugated antibody
Accession
http://www.uniprot.org/uniprot/P47900
http://www.uniprot.org/uniprot/P49651
http://www.uniprot.org/uniprot/P59902
Purity
Whole serum
Clonality
Polyclonal
Specificity
Specific for P2RY1.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Amount: 100ul
Available: In stock
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