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Rabbit antibody to AMPA2

ArtNr OSA00236W
Hersteller Osenses
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias GRIA2, Glutamate receptor 2, GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2, GLUR2
Similar products GRIA2, Glutamate receptor ionotropic, GLUR2, GluR-K2, Glutamate receptor 2, GluR-B, GluR-2, AMPA 2, AMPA-selective glutamate receptor 2
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Also known
GRIA2, Glutamate receptor 2, GluR-2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, AMPA-selective glutamate receptor 2, GLUR2
Target
FUNCTION: Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist.
Subcellular location: Cell membrane; Multi-pass membrane protein. Cell junction a€C synapse a€C postsynaptic cell membrane; Multi-pass membrane protein.
Tissue specificity: Detected in brain cortex, hippocampus and cerebellum (at protein level). Detected in hippocampus.
Spcs X-react.
Human, mouse, rat. Other species not yet tested.
Applications info
IHC, WB. A dilution of 1 : 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Koehler M, et al. J. Biol. Chem. 269:17367-17370(1994)
Limitation
For research use only
Immunogen
A synthetic peptide from human AMPA2 conjugated to blue carrier protein was used as the antigen.
Conjugate
Unconjugated antibody
Accession
http://www.uniprot.org/uniprot/P23819
http://www.uniprot.org/uniprot/P42262
http://www.uniprot.org/uniprot/P19491
Purity
Whole serum
Clonality
Polyclonal
Specificity
Specific for AMPA2.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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