Vergleich

Rabbit antibody to AQP4

ArtNr OSA00155W
Hersteller Osenses
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Aquaporin-4, AQP-4, AQP4, Aquaporin4, WCH4, MIWC
Similar products AQP4, Aquaporin-4, AQP-4, WCH4, MIWC, Aquaporin4
Lieferbar
Also known
Aquaporin-4, AQP-4, AQP4, Aquaporin4, WCH4, MIWC
Target
FUNCTION: Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system. It is expressed predominantly in the ependymal cell lining the aqueductal system and over the space of the brain in contact with the subarachnoid space, as cerebrospinal fluid fills these structures it may facilitate water balance between brain parenchyma and the fluid compartment. In the plasma membranes of the neurons of the paraventricular and supraoptic nuclei, it may mediate rapid changes in cell volume in response to local shifts in extracellular osmolarity.
Tissue specificity: Abundant in mature brain but only weakly detectable in eye, kidney, intestine, and lung.
SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein
Spcs X-react.
Mouse, rat. Other species not yet tested but expected to work in marmoset and human.
Applications info
IHC, WB. A dilution of 1 : 1000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Zelenin S, et al. Pediatr. Res. 48:335-339(2000)
Limitation
For research use only
Immunogen
A synthetic peptide from mouse AQP4 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat.
Conjugate
Unconjugated antibody
Accession
http://www.uniprot.org/uniprot/P55088
http://www.uniprot.org/uniprot/P47863
Purity
Whole serum
Clonality
Polyclonal
Specificity
Specific for AQP4.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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