PUF60 Antibody (N-term) Blocking Peptide

The protein encoded by this gene is a Ro RNP-bindingprotein. It interacts with Ro RNPs and their interaction is thoughtto represent a gain of function for Ro RNPs. This protein alsoforms a ternary complex with far upstream element (FUSE) andFUSE-binding protein. It can repress a c-myc reporter via the FUSE.It is also known to target transcription factor IIH and inhibitactivated transcription. This gene is implicated in the xerodermapigmentosum disorder. There are two alternatively splicedtranscript variants of this gene encoding different isoforms. Thereseems to be evidence of multiple polyadenylation sites for thisgene.

22827

Synthetic peptide