ACTN2 Antibody (C-term) Blocking Peptide

Alpha actinins belong to the spectrin gene superfamilywhich represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alphaactinin is an actin-binding protein with multiple roles indifferent cell types. In nonmuscle cells, the cytoskeletal isoformis found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to theZ-disc and analogous dense bodies, where they help anchor themyofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal andcardiac muscles.

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Synthetic peptide