HIST1H2BB/HIST1H2BE Antibody (N-term) Blocking Peptide

Histones are basic nuclear proteins that are responsiblefor the nucleosome structure of the chromosomal fiber ineukaryotes. Nucleosomes consist of approximately 146 bp of DNAwrapped around a histone octamer composed of pairs of each of thefour core histones (H2A, H2B, H3, and H4). The chromatin fiber isfurther compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatinstructures. This gene is intronless and encodes a member of thehistone H2B family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This geneis found in the large histone gene cluster on chromosome6p22-p21.3.

3018

Synthetic peptide