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Cynomolgus CLEC12A / MICL / CLL-1 Protein, His Tag

Cynomolgus CLEC12A / MICL / CLL-1 Protein, His Tag

ArtNr	CLA-C5246-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Quantity options	100 ug 1 mg
Kategorie	Peptides & Proteins Amino Acids
Typ	Proteins
Format	Solid
Specific against	Monkey (Cynomolgus, Simian)
Host	HEK293
Konjugat/Tag	Unconjugated, HIS
Purity	90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371
Versandbedingung	Raumtemperatur
Lieferbar
Specificity	Cynomolgus
Manufacturer - Category	Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag	N-10×His, Unconjugated
Manufacturer - Species	Cynomolgus
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	25.5 kDa
Description	Cynomolgus CLEC12A, His Tag (CLA-C5246) is expressed from human 293 cells (HEK293). It contains AA His 32 - Ala 232 (Accession # A0A2K5WXQ6-1).
Background	CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
Molecule	CLEC12A
Exp Region	His 32 - Ala 232
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 25.5 kDa. The protein migrates as 34-46 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

CLA-C5246-100ug-datasheet.pdf

CLA-C5246-100ug-safety-datasheet.pdf