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Cynomolgus CLEC12A / MICL / CLL-1 Protein, His Tag

Cynomolgus CLEC12A / MICL / CLL-1 Protein, His Tag

Item no.	CLA-C5246-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 1 mg
Category	Peptides & Proteins Amino Acids
Type	Proteins
Format	Solid
Specific against	Monkey (Cynomolgus, Simian)
Host	HEK293
Conjugate/Tag	Unconjugated, HIS
Purity	90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CLEC12A,MICL,CLL-1,CLL1,DCAL2,DCAL-2,CD371
Shipping condition	Room temperature
Available
Specificity	Cynomolgus
Manufacturer - Category	Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag	N-10×His, Unconjugated
Manufacturer - Species	Cynomolgus
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	25.5 kDa
Description	Cynomolgus CLEC12A, His Tag (CLA-C5246) is expressed from human 293 cells (HEK293). It contains AA His 32 - Ala 232 (Accession # A0A2K5WXQ6-1).
Background	CLEC12A (C-type lectin domain family 12 member A) is also known as CLL1, DCAL2, MICL. Clec12a is an inhibitory receptor for uric acid crystals that regulates inflammation in response to cell death. Cell surface receptor that modulates signaling cascades and mediates tyrosine phosphorylation of target MAP kinases. Evidence of distinct disease propagating stem cells in myelodysplastic syndrome (MDS) has emerged in recent years. The role of CLEC12A in MDS, however, remains to be elucidated. Furthermore, CLEC12A has been proposed as a promising marker of leukaemic stem cells in AML.
Molecule	CLEC12A
Exp Region	His 32 - Ala 232
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 25.5 kDa. The protein migrates as 34-46 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CLA-C5246-100ug-datasheet.pdf

CLA-C5246-100ug-safety-datasheet.pdf