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Fluorescent Human EDNRB Full Length Protein (VLP)

Fluorescent Human EDNRB Full Length Protein (VLP)

ArtNr	EDB-HF2G4-500ug
Hersteller	ACROBiosystems
Menge	250 ug x 2
Quantity options	100 ug 20 ug 250 ug x 2
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	GFP
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	GFP Tag, GFP Fusion
Shipping Temperature	Dry ice
Storage Conditions	-70°C, avoid light
Molecular Weight	48.6 kDa \| 83.1 kDa
Manufacturer - Format	Liquid
Description	Endothelin Receptor B (EDNRB) is a type of G protein-coupled Receptor with the N-terminus located outside the cell. It's widespread in the human body. EDNRB binds to ET and transmits information into the cell through the intracellular Ca2+ phospholipid-dependent protein kinase second messenger system, which promotes the rapid release of calcium in the endoplasmic reticulum and sarcoplasmic reticulum, resulting in the rapid increase of intracellular calcium concentration. Endothelin exerts its biological effects through its receptor (ETR). Endothelin and ETR constitute the endothelin axis. Endothelin axis has pro-tumor effects in various tumors including malignant melanoma (MM), including promoting tumor growth, anti-apoptosis, promoting angiogenesis and promoting tumor metastasis.
Background	Endothelin Receptor B (EDNRB) is a type of G protein-coupled Receptor with the N-terminus located outside the cell. It's widespread in the human body. EDNRB binds to ET and transmits information into the cell through the intracellular Ca2+ phospholipid-dependent protein kinase second messenger system, which promotes the rapid release of calcium in the endoplasmic reticulum and sarcoplasmic reticulum, resulting in the rapid increase of intracellular calcium concentration. Endothelin exerts its biological effects through its receptor (ETR). Endothelin and ETR constitute the endothelin axis. Endothelin axis has pro-tumor effects in various tumors including malignant melanoma (MM), including promoting tumor growth, anti-apoptosis, promoting angiogenesis and promoting tumor metastasis.
Molecule	EDNRB
Exp Region	Glu 27 - Ser 442
Characteristics	This protein carries a GFP tag.
Endotoxin	1.0 EU per μg
Buffer	PBS, Arginine, pH7.4
Stability	● The product MUST be stored at -70°C or lower upon receipt ● -70°C for 12 months under sterile conditions.
Protectant	trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

EDB-HF2G4-500ug-datasheet.pdf

EDB-HF2G4-500ug-safety-datasheet.pdf