tPA

ArtNr	enz-263-1mg
Hersteller	ProSpec
Menge	1 mg
Quantity options	100 ug 1 mg 20 ug
Kategorie	Food Safety Proteins Peptides & Proteins Enzymes
Typ	Enzymes
Format	Lyophilized
Specific against	Human (Homo sapiens)
Purity	Greater than 98.0% as determined by:<BR>(a) Analysis by RP-HPLC.<BR>(b) Analysis by SDS-PAGE.
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Alias	tPA,Tissue-type plasminogen activator,EC 3 4 21 68,tPA,t-PA,t-plasminogen activator,TPA,T-PA,DKFZp686I03148
Similar products	tPA
Lieferbar
Manufacturer - Category	ENZYMES
Storage Conditions	Lyophilized t-PA although stable at room temperature for 3 weeks, should be stored desiccated below -18C. Upon reconstitution tPA should be stored at 4C between 2-7 days and for future use below -18C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Description	Recombinant Human Tissue Plasminogen Activator
Formulation	Each mg of t-PA contains 1.7 gr L-arginine, 0.5 gr phosphoric acid and 4 mg tween 80.
Introduction	Tissue plasminogen activator (abbreviated PLAT or tPA) is a secreted serine proteasewhich converts the proenzymeplasminogento plasmin, a fibrinolyticenzyme. Plasminogen is synthesized as a single chain which is cleaved by PLAT into the two chain disulfide linked plasmin. This enzyme plays a role in cell migrationand tissue remodeling. Increased enzymatic activity causes hyperfibrinolysis, which manifests as excessive bleeding, decreased activity leads to hypofibrinolysiswhich can result in thrombosisor embolism.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Manufacturer - Format	Sterile Filtered White lyophilized (freeze-dried) powder.

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enz-263-1mg-safety-datasheet.pdf