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Human CD20 (Full Length) Protein-VLP Europäischer Partner

ArtNr 11007-HNAH-100
Hersteller Sino Biological
Menge 100 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Specific against Human (Homo sapiens)
Host HEK293 cells
Dry ice Yes
Sequence Met1-Pro297
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias B1,Bp35,CD20,CVID5,FMC7,LEU-16,S7
Versandbedingung Trockeneis
Lieferbar
Manufacturer - Type
Protein
Manufacturer - Conjugate / Tag
Native
Shipping Temperature
Dry ice
Storage Conditions
-20C
Molecular Weight
The recombinant human CD20 predicts a molecular mass of 33.08 kDa.
Antigen molecule name
MS4A1
Buffer
Supplied as sterile solution 50mM HEPES, 150mM NaCl, 10% Trehalose, pH 7.2.
Protein Construction
A DNA sequence encoding the human CD20 (P11836) (Met1-Pro297) was expressed.
Bio-Activity
1.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP (Cat: 11007-HNAH) at 5 μg/mL (100 μL/well) can bind Obinutuzumab, the EC50 is 1.0-3.0 ng/mL.(Routinely tested)
2.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP (Cat: 11007-HNAH) at 5 μg/mL (100 μL/well) can bind Ofatumumab, the EC50 is 1.4-9.4 ng/ mL.(QC tested)
3.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP (Cat: 11007-HNAH) at 5 μg/mL (100 μL/well) can bind Rituximab, the EC50 is 6-18 ng/mL.(QC tested)
4.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP from competitor A and SINO at 5 μg/mL (100 μL/well) can bind anti-CD20(Research grade Obinutuzumab biosimilar), the EC50  is 3 ng/mL and 1.7 ng/mL, respectively. The results demonstrated that SINO CD20 (Cat. No. 11007-HNAH) has a higher binding capacity than that of competitor A (Routinely tested).
5.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP from competitor A and SINO at 5 μg/mL (100 μL/well) can bind anti-CD20(Research grade Ofatumumab biosimilar), the EC50  is 10.3 ng/mL and 5.4 ng/mL, respectively. The results demonstrated that SINO CD20 (Cat. No. 11007-HNAH) has a higher binding capacity than that of competitor A (Routinely tested).
5.Immobilized Recombinant Human CD20 (Full Length) Protein-VLP from competitor A and SINO at 5 μg/mL (100 μL/well) can bind anti-CD20(Research grade Rituximab biosimilar), the EC50  is 19.8 ng/mL and 34.9 ng/mL, respectively. The results demonstrated that SINO CD20 (Cat. No. 11007-HNAH) has a higher binding capacity than that of competitor A (Routinely tested).
N-terminus
Met 1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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