Human TRAIL protein

ArtNr	ABK-PRP1028-1mg
Hersteller	Abbkine Scientific
Menge	1 mg
Quantity options	100 ug 10 ug 1 mg 50 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins
Format	Lyophilized
Specific against	other
Purity	>92% as determined by SDS-PAGE
Sequence	Amino acid sequence derived from human TRAIL isoform (P50591-1) (Val114-Gly281) was expressed.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Tumor Necrosis Factor Ligand Superfamily Member 10,Apo-2 Ligand,Apo-2L,TNF-Related Apoptosis-Inducing Ligand,Protein TRAIL,CD253,TNFSF10,APO2L,TRAIL
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Cytokine
Manufacturer - Category	Cytokines and proteins
Manufacturer - Conjugate / Tag	TRAIL
Shipping Temperature	The product is shipped at ambient temperature.
Storage Conditions	Lyophilized Human TRAIL proteinshould be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.20% HSA or BSA). Please prevent freeze-thaw cycles.
Molecular Weight	19.5 KD
Background	The protein encoded by Tumor necrosis factor-related apoptosis inducing ligand (TRAIL) is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This protein preferentially induces apoptosis in transformed and tumor cells, but does not appear to kill normal cells although it is expressed at a significant level in most normal tissues. The binding of this protein to its receptors has been shown to trigger the activation of MAPK8/JNK, caspase 8, and caspase 3.
Description	Human TRAIL protein, expressed in E. coli
Formulation	Lyophilized from sterile 20 mM Tris, 150 mM NaCl, pH 8.0.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Features & Benefits	Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.
Usage Notes	Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human TRAIL protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Preparation method	E. coli
Activity	Measured by its ability to induce cytotoxicity in the presence of the metabolic inhibitor actinomycin D.The ED50 for this effect is 26.27 ng/mL.
Protein length	The recombinant human TRAIL consists of 168 amino acids and has a predicted molecular mass of 19.5 KDa.
Manufacturer - Search Terms	Tumor Necrosis Factor Ligand Superfamily Member 10, Apo-2 Ligand, Apo-2L, TNF-Related Apoptosis-Inducing Ligand, Protein TRAIL, CD253, TNFSF10, APO2L, TRAIL

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Menge: 1 mg

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Lieferung vsl. bis 04.12.2025