Mouse IL-13 protein, His tag (Animal-Free)

The recombinant mouse IL-13 protein consists of 118 amino acids and predicts a molecular mass of 12.7 kD.The apparent molecular mass of the mouse IL13 is approximately 15-30 kDa in SDS-PAGE under reducing conditions due to glycosylation.

>95% as determined by SDS-PAGE

Endotoxin: < 1 EU per ug of the protein as determined by the LAL method.

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized mouse IL-13 protein in the buffer which we provide not less than 100 ug/mL, which can then be further diluted to other aqueous solutions.

The product is shipped at ambient temperature.

Interleukin(IL)-13, a cytokine produced by T helper 2 (Th2) cells, is a powerful inhibitor of macrophage functions, including surface expression of CD14 and production of IL-1 and tumor necrosis factor (TNF)-alpha. Interleukin (IL) -13 synergizes with IL2 in regulating interferon-gamma synthesis . It may be critical in regulating inflammatory and immune responses .Mouse IL13 shares 58% sequence identity with human protein and exhibits cross-species activity.IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. It was also thought to be functionally redundant with IL-4.

ALRHMGC116789; BHR1interleukin-13; IL13; IL-13; IL-13MGC116788; interleukin 13; MGC116786; NC30; P600

IL-13