Mouse IL-13 protein, His tag (Animal-Free)

Cytokine

IL-13

Lyophilized Mouse IL-13 protein, His tag (Animal-Free)should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.119% HSA or BSA). Please prevent freeze-thaw cycles.

Interleukin(IL)-13, a cytokine produced by T helper 2 (Th2) cells, is a powerful inhibitor of macrophage functions, including surface expression of CD14 and production of IL-1 and tumor necrosis factor (TNF)-α. Interleukin (IL) -13 synergizes with IL-2 in regulating interferon-gamma synthesis . It may be critical in regulating inflammatory and immune responses .Mouse IL-13 shares 58% sequence identity with human protein and exhibits cross-species activity.IL-13 was first recognized for its effects on B cells and monocytes, where it upregulated class II expression, promoted IgE class switching and inhibited inflammatory cytokine production. It was also thought to be functionally redundant with IL-4.

Lyophilized from sterile PBS, pH 7.4.

Endotoxin: < 1 EU per µg of the protein as determined by the LAL method.

HEK293 Cells

ALRHMGC116789, BHR1interleukin-13, IL13, IL-13, IL-13MGC116788, interleukin 13, MGC116786, NC30, P600