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Human ANGPTL7 / CDT6 Protein, Mouse IgG2a Fc Tag

Human ANGPTL7 / CDT6 Protein, Mouse IgG2a Fc Tag

ArtNr	AN7-H5252-1mg
Hersteller	ACROBiosystems
Menge	200 ug x 5
Quantity options	100 ug 200 ug x 5
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Isotype	IgG2a
Konjugat/Tag	Unconjugated, C-mFc
Purity	90%
Citations	(1) Peek R., et al., 1998, Invest. Opthalmol. Visual Sci. 39 (10): 1782-1788. (2) Peek R., et al., 2002, J. Biol. Chem. 277 (1): 686-693. (3) Kuchtey, J. et al., 2008, Invest. Opthalmol. Visual Sci. 49 (8): 3438-3448.
NCBI	NP_066969.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ANGPTL7,CDT6
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-mFc(mIgG2a), Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	64.1 kDa
Manufacturer - Format	Powder
Description	Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.
Background	Angiopoietin-like 7 (ANGPTL7) is also known as Corneal-Derived Transcript 6 (CDT6), and is a secreted glycoprotein that is structurally related to the angiopoietins. It is expressed in the corneal stroma, trabecular meshwork, and sclera and is elevated in glaucoma aqueous humor. Recently, ANGPTL proteins, including ANGPTL-2, -3, -4, -5 and -7, are identified as growth factors in combination with SCF, Thrombopoietin, IGF-II and FGF acidic that enhance the expansion and engraftment of human and mouse hematopoietic stem cells.
Molecule	ANGPTL7
Exp Region	Gln 27 - Pro 346
Characteristics	This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 64.1 kDa. The protein migrates as 60 kDa and 76 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	Tris with Glycine, Arginine and NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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AN7-H5252-1mg-datasheet.pdf

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