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Human C1q R1 / CD93 Protein, His Tag (MALS verified) Europäischer Partner

ArtNr C11-H5228-50ug
Hersteller ACROBiosystems
Menge 50 ug
Quantity options 250 ug x 4 50 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag Unconjugated, HIS
Purity 90%
Citations (1) Ghebrehiwet B., et al., 1997, J. Immunol. 159:1429-1436. (2) Nepomuceno R.R., et al., 1999, J. Immunol. 162:3583-3589. (3) Kittlesen D.J., et al., 2000, J. Clin. Invest. 106:1239-1249.
NCBI AAH28075
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD93,CDw93,C1QR1,MXRA4,C1qR,C1qR(P),C1qRP,ECSM3
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-7xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
59.2 kDa
Manufacturer - Species
Human
Manufacturer - Format
Powder
Description
CD antigen CD93 is also known as Complement component C1q receptor (C1QR1). which belongs to the Group XIV C-Type lectin family, a group containing two other members, endosialin (CD248) and thrombomodulin. CD93 contains one C-type lectin domain and five EGF-like domains. CD93 is highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. CD93 is receptor for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). CD93 may mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens and may play a role in intercellular adhesion.
Background
CD antigen CD93 is also known as Complement component C1q receptor (C1QR1). which belongs to the Group XIV C-Type lectin family, a group containing two other members, endosialin (CD248) and thrombomodulin. CD93 contains one C-type lectin domain and five EGF-like domains. CD93 is highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. CD93 is receptor for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). CD93 may mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens and may play a role in intercellular adhesion.
Molecule
C1q R1
Exp Region
Thr 22 - Lys 580
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 59.2 kDa. The protein migrates as 80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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