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Human C1q R1 / CD93 Protein, His Tag (MALS verified)

Human C1q R1 / CD93 Protein, His Tag (MALS verified)

Item no.	C11-H5228-50ug
Manufacturer	ACROBiosystems
Amount	50 ug
Quantity options	250 ug x 4 50 ug
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated, HIS
Purity	90%
Citations	(1) Ghebrehiwet B., et al., 1997, J. Immunol. 159:1429-1436. (2) Nepomuceno R.R., et al., 1999, J. Immunol. 162:3583-3589. (3) Kittlesen D.J., et al., 2000, J. Clin. Invest. 106:1239-1249.
NCBI	AAH28075
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD93,CDw93,C1QR1,MXRA4,C1qR,C1qR(P),C1qRP,ECSM3
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-7xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	59.2 kDa
Manufacturer - Species	Human
Manufacturer - Format	Powder
Description	CD antigen CD93 is also known as Complement component C1q receptor (C1QR1). which belongs to the Group XIV C-Type lectin family, a group containing two other members, endosialin (CD248) and thrombomodulin. CD93 contains one C-type lectin domain and five EGF-like domains. CD93 is highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. CD93 is receptor for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). CD93 may mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens and may play a role in intercellular adhesion.
Background	CD antigen CD93 is also known as Complement component C1q receptor (C1QR1). which belongs to the Group XIV C-Type lectin family, a group containing two other members, endosialin (CD248) and thrombomodulin. CD93 contains one C-type lectin domain and five EGF-like domains. CD93 is highly expressed in endothelial cells, platelets, cells of myeloid origin, such as monocytes and neutrophils. CD93 is receptor for C1q, mannose-binding lectin (MBL2) and pulmonary surfactant protein A (SPA). CD93 may mediate the enhancement of phagocytosis in monocytes and macrophages upon interaction with soluble defense collagens and may play a role in intercellular adhesion.
Molecule	C1q R1
Exp Region	Thr 22 - Lys 580
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 59.2 kDa. The protein migrates as 80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

C11-H5228-50ug-datasheet.pdf

C11-H5228-50ug-safety-datasheet.pdf