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Cynomolgus CD3 delta Protein, His Tag Europäischer Partner

ArtNr CDD-C52H8-100ug
Hersteller ACROBiosystems
Menge 100 ug
Quantity options 100 ug 500 ug x 2
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Monkey (Cynomolgus, Simian)
Host HEK293
Konjugat/Tag Unconjugated
Purity 90%
Citations (1) Gil J, et al., 2011, J Clin Invest, 121(10):3872-6. (2) Lu X, et al.,2011, Hematology, 16(3):185-9. (3) Kim ST, et al., 2010, J Immunol, 185(5):2951-9.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD3D,CD3-DELTA,T3D
Versandbedingung Raumtemperatur
Lieferbar
Specificity Cynomolgus
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-6xHis, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
14.3 kDa
Manufacturer - Format
Powder
Description
T-cell surface glycoprotein CD3 delta, also known as CD3D. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.
Background
T-cell surface glycoprotein CD3 delta, also known as CD3D. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.
Molecule
CD3 delta
Exp Region
Phe 22 - Ala 105
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.3 kDa. The protein migrates as 20-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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