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Cynomolgus CD3 delta Protein, His Tag

Cynomolgus CD3 delta Protein, His Tag

Item no.	CDD-C52H8-100ug
Manufacturer	ACROBiosystems
Amount	100 ug
Quantity options	100 ug 500 ug x 2
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Monkey (Cynomolgus, Simian)
Host	HEK293
Conjugate/Tag	Unconjugated
Purity	90%
Citations	(1) Gil J, et al., 2011, J Clin Invest, 121(10):3872-6. (2) Lu X, et al.,2011, Hematology, 16(3):185-9. (3) Kim ST, et al., 2010, J Immunol, 185(5):2951-9.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD3D,CD3-DELTA,T3D
Shipping Condition	Room temperature
Available
Specificity	Cynomolgus
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	C-6xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	14.3 kDa
Manufacturer - Format	Powder
Description	T-cell surface glycoprotein CD3 delta, also known as CD3D. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.
Background	T-cell surface glycoprotein CD3 delta, also known as CD3D. CD3D, together with CD3- epsilon(CD3E) , CD3-gamma and CD3-zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T cell receptor-CD3 complex. T cell receptor-CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.When antigen presenting cells (APCs) activate T-cell receptor (TCR), TCR-mediated signals are transmitted across the cell membrane by the CD3 chains CD3D, CD3E, CD3G and CD3Z.
Molecule	CD3 delta
Exp Region	Phe 22 - Ala 105
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 14.3 kDa. The protein migrates as 20-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

CDD-C52H8-100ug-datasheet.pdf

CDD-C52H8-100ug-safety-datasheet.pdf