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Human Galectin-4 / LGALS4 / L36LBP Protein, His Tag

Human Galectin-4 / LGALS4 / L36LBP Protein, His Tag

ArtNr	GA4-H5246-1mg
Hersteller	ACROBiosystems
Menge	200 ug x 5
Quantity options	100 ug 200 ug x 5
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated
Purity	95%
Citations	(1) Barondes SH., et al., 1994, J. Biol. Chem. 269 (33): 20807-20810. (2) Yang, RY., et al., 2008, Expert Rev. Mol. Med. 10: e17. (3) Ideo H., et al., 2007, J. Biol. Chem. 282 (29): 21081-21089.
NCBI	NP_006140.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LGALS4,L36LBP,Gal-4,Antigen NY-CO-27,Lactose-binding lectin 4
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-9xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	38.1 kDa
Manufacturer - Format	Powder
Description	Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein). The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer.
Background	Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein). The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer.
Molecule	Galectin-4
Exp Region	Met 1 - Ile 323
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 38.1 kDa. The protein migrates as 40-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM HEPES, 150 mM NaCl, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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GA4-H5246-1mg-datasheet.pdf

GA4-H5246-1mg-safety-datasheet.pdf