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Human Galectin-4 / LGALS4 / L36LBP Protein, His Tag

Human Galectin-4 / LGALS4 / L36LBP Protein, His Tag

Item no.	GA4-H5246-1mg
Manufacturer	ACROBiosystems
Amount	200 ug x 5
Quantity options	100 ug 200 ug x 5
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Format	Solid
Specific against	Human (Homo sapiens)
Host	HEK293
Conjugate/Tag	Unconjugated
Purity	95%
Citations	(1) Barondes SH., et al., 1994, J. Biol. Chem. 269 (33): 20807-20810. (2) Yang, RY., et al., 2008, Expert Rev. Mol. Med. 10: e17. (3) Ideo H., et al., 2007, J. Biol. Chem. 282 (29): 21081-21089.
NCBI	NP_006140.1
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	LGALS4,L36LBP,Gal-4,Antigen NY-CO-27,Lactose-binding lectin 4
Shipping Condition	Room temperature
Available
Manufacturer - Category	Protein
Manufacturer - Conjugate / Tag	N-9xHis, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	38.1 kDa
Manufacturer - Format	Powder
Description	Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein). The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer.
Background	Galectin-4 (Gal-4), also known as L36LBP (L-36 lactose-binding protein). The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. Galectin-4 expression is concentrated within microvilli in the gastrointestinal epithelium, where it can interact with CD3 and bind activated T cells in the lamina propria during intestinal inflammation. LGALS4 is an S-type lectin that is strongly underexpressed in colorectal cancer.
Molecule	Galectin-4
Exp Region	Met 1 - Ile 323
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 38.1 kDa. The protein migrates as 40-44 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM HEPES, 150 mM NaCl, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state ● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

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GA4-H5246-1mg-datasheet.pdf

GA4-H5246-1mg-safety-datasheet.pdf