Vergleich

Cynomolgus Glypican 3 / GPC3 Protein, Fc Tag Europäischer Partner

ArtNr GP3-C5256-100ug
Hersteller ACROBiosystems
Menge 100 ug
Quantity options 100 ug 500 ug x 2
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Monkey (Cynomolgus, Simian)
Host HEK293
Konjugat/Tag Unconjugated, Fc
Purity 90%
Citations (1) Davoodi J., et al., 2007, Proteomics 7:2300-2310. (2) Veugelers M., et al., 2000, Hum. Mol. Genet. 9:1321-1328.
NCBI XP_005594665.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias GPC3,OCI5,Glypican-3,GTR2-2,MXR7,DGSX,SDYS ,SGB,SGBS,SGBS1
Versandbedingung Raumtemperatur
Lieferbar
Specificity Cynomolgus
Manufacturer - Category
Protein
Manufacturer - Conjugate / Tag
C-Fc, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
38.1 kDa & 49.4 kDa
Manufacturer - Format
Powder
Description
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Background
Glypican-3 (GPC3) is also known as Intestinal protein OCI-5, GTR2-2, MXR7, which belongs to the glypican family. Glypican 3 / GPC-3 is highly expressed in lung, liver and kidney. Glypican-3 inhibits the dipeptidyl peptidase activity of DPP4. Glypican-3 may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and also may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function.
Molecule
Glypican 3
Exp Region
Gln 25 - Arg 358 & Ser 359 - His 559
Characteristics
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 38.1 kDa & 49.4 kDa. The protein migrates as 40 kDa, 60 kDa and 100-120 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin
1.0 EU per μg
Buffer
Tris with Glycine,  Arginine and NaCl,  pH7.5
Stability
● -20°C to -70°C for 12 months in lyophilized state
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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