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Biotinylated Cynomolgus IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, Fc,Avitag™&Fc,Avitag™ (MALS verified)

Biotinylated Cynomolgus IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, Fc,Avitag™&Fc,Avitag™ (MALS verified)

Hersteller	ACROBiosystems
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	Monkey
Format	Powder
Menge	200ug
Host	HEK293
ArtNr	ILG-C82F6-200ug
Konjugat/Tag	Fc; AVI
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Bioactivity Legend 1	Immobilized Human IL-2, His Tag (Cat. No. IL2-H52H8) at 5 ug/mL (100 uL/well) can bind Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG, Fc, Avitag&Fc, Avitag (Cat. No. ILG-C82F6) with a linear range of 8-125 ng/mL (QC tested).
Buffer	PBS, pH7.4
Characteristics	Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG, Fc, Avitag&Fc, Avitag is produced by co-expression of IL-2RB and IL-2RA and IL-2RG, has a calculated MW of 53.0 kDa (IL-2RB) and 80.0 kDa (IL-2RA&IL-2RG). Subunit IL-2RB is fused with a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag) and subunit IL-2RA&IL-2RG is fused with a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag). The reducing (R) protein migrates as 65-70 kDa and 115-130 kDa respectively due to glycosylation.
Description	Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
Endotoxin Level	Less than 1.0 EU per ug by the LAL method.
Exp Region	Ala 27 - Thr 240 (IL-2RB) & Glu 22 - Glu 238 (IL-2RA) & Leu 23 - Pro 255 (IL-2RG)
Expression System	HEK293
Molecular Weight	53.0 kDa & 80.0 kDa
Molecule	IL-2 R beta & IL-2 R alpha & IL-2 R gamma
SDS-PAGE Legend	Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG, Fc, Avitag&Fc, Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Storage	-20C
Host Information	Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG, Fc, Avitag&Fc, Avitag (ILG-C82F6) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Thr 240 (IL-2RB) & Glu 22 - Glu 238 (IL-2RA) & Leu 23 - Pro 255 (IL-2RG) (Accession # Q38J85-1 (IL-2RB) & A0A2K5UYC9-1 (IL-2RA) & Q38JL2-1 (IL-2RG)).

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 200ug

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Lieferung vsl. bis 06.06.2024

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