« Back
Home /
Biotinylated Cynomolgus IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, Fc,Avitag™&Fc,Avitag™ (MALS verified)

Biotinylated Cynomolgus IL-2 R beta&IL-2 R alpha&IL-2 R gamma Protein, Fc,Avitag™&Fc,Avitag™ (MALS verified)

Manufacturer	ACROBiosystems
Category	Peptides & Proteins Recombinant Proteins
Type	Proteins Recombinant
Specific against	Monkey
Format	Powder
Amount	200ug
Host	HEK293
Item no.	ILG-C82F6-200ug
Conjugate/Tag	Fc; AVI
eClass 6.1	34160400
eClass 9.0	42020190
Available
Alias	IL-2 R beta & IL-2 R alpha & IL-2 R gamma
Purity	>95% as determined by reduced SDS-PAGE.
Bioactivity Legend 1	Immobilized Human IL-2, His Tag (Cat. No. IL2-H52H8) at 5 ug/mL (100 uL/well) can bind Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG, Fc, Avitag&Fc, Avitag (Cat. No. ILG-C82F6) with a linear range of 8-125 ng/mL (QC tested).
Buffer	PBS, pH7.4
Characteristics	Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG, Fc, Avitag&Fc, Avitag is produced by co-expression of IL-2RB and IL-2RA and IL-2RG, has a calculated MW of 53.0 kDa (IL-2RB) and 80.0 kDa (IL-2RA&IL-2RG). Subunit IL-2RB is fused with a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag) and subunit IL-2RA&IL-2RG is fused with a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag). The reducing (R) protein migrates as 65-70 kDa and 115-130 kDa respectively due to glycosylation.
Description	Both Interleukin-2 receptor subunit beta and Interleukin-2 receptor subunit gamma are receptor for interleukin-2. Common subunit for the receptors for a variety of interleukins. Interacts with SHB upon interleukin stimulation. Probably in association with IL15RA, involved in the stimulation of neutrophil phagocytosis by IL15. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2. IL2R exists in 3 different forms: a high affinity dimer, an intermediate affinity monomer (beta subunit), and a low affinity monomer (alpha subunit). The high and intermediate affinity forms also associate with a gamma subunit.
Endotoxin Level	Less than 1.0 EU per ug by the LAL method.
Exp Region	Ala 27 - Thr 240 (IL-2RB) & Glu 22 - Glu 238 (IL-2RA) & Leu 23 - Pro 255 (IL-2RG)
Expression System	HEK293
Molecular Weight	53.0 kDa & 80.0 kDa
Molecule	IL-2 R beta & IL-2 R alpha & IL-2 R gamma
SDS-PAGE Legend	Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG, Fc, Avitag&Fc, Avitag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%.
Storage	-20C
Host Information	Biotinylated Cynomolgus IL-2RB&IL-2RA&IL-2RG, Fc, Avitag&Fc, Avitag (ILG-C82F6) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Thr 240 (IL-2RB) & Glu 22 - Glu 238 (IL-2RA) & Leu 23 - Pro 255 (IL-2RG) (Accession # Q38J85-1 (IL-2RB) & A0A2K5UYC9-1 (IL-2RA) & Q38JL2-1 (IL-2RG)).

Note: The presented information and documents (Manual, Product Datasheet, Safety Datasheet and Certificate of Analysis) correspond to our latest update and should serve for orientational purpose only. We do not guarantee the topicality. We would kindly ask you to make a request for specific requirements, if necessary.

All products are intended for research use only (RUO). Not for human, veterinary or therapeutic use.

Request Data Sheet

Request product datasheet

Request safety datasheet

Simple Order Order Subscription

Amount: 200ug

available

Delivery expected until 7/5/2024

Express Delivery: Save 3 days

Compare

Add to wishlist

Recommend by mail